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Hydroxyl PEG Amine, HCl Salt
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產品名稱:

Hydroxyl PEG Amine, HCl Salt

產品代號:
HO-PEG5000-NH2HCl
產品純度:
≥ 95%
分子量:
1000 Da,2000 Da,3500 Da, 5000 Da, 7500 Da,10000 Da, 20000 Da,等
產品編號:
A5015
沒有此類產品
產品描述

  鍵凱科技提供高品質羥基PEG胺,產品取代率大于等于95%。

  鍵凱科技生產的異雙功能羥基PEG胺產品通常用作兩種不同化學物質的交聯劑或間隔物。此異功能PEG衍生物中的PEG部分可提供水溶性、生物相容性及柔性。此產品專門應用于抗體偶聯藥物(ADC’s)的開發。

  鍵凱科技提供HO-PEG-NH2HCl分子量1000 Da,2000 Da,3500 Da, 5000 Da, 7500 Da,10000 Da, 20000 Da的產品1克和5克包裝。

  鍵凱科技提供分裝服務,需要收取分裝費用,如果您需要分裝為其他規格請與我們聯系。

  鍵凱科技同時提供其他分子量的HO-PEG-NH2HCl衍生物產品,如你需要請與我司[email protected]聯系。

  鍵凱科技提供大批量生產產品及GMP級別產品,如需報價請與我們聯系。

References:

1. Xu, Y., et al., Triphenylphosphonium-modified poly (ethylene glycol)-poly (ε-caprolactone) micelles for mitochondria-targeted gambogic acid delivery, International Journal of Pharmaceutics, 2017, 522(1):21-33.

2. Lu, L., et al., Anisamide-Decorated pH-Sensitive Degradable Chimaeric Polymersomes Mediate Potent and Targeted Protein Delivery to Lung Cancer Cells, Biomacromolecules, 2015.

3. Hoang, N.B.,Polymeric micelles as a diagnostic tool for image-guided drug delivery and radiotherapy of HER2 overexpressing breast cancer, Diss. University of Toronto, 2014.

4. Hoang, B., et al., Active Targeting of Block Copolymer Micelles with Trastuzumab Fab Fragments and Nuclear Localization Signal Leads to Increased Tumor Uptake and Nuclear Localization in HER2-Overexpressing Xenografts, Mol. Pharmaceutics, 2013, 10(11), p: 4229–4241.

5. Yang, Z., et al., Targeted delivery of 10-hydroxycamptothecin to human breast cancers by cyclic RGD-modified lipid–polymer hybrid nanoparticles, Biomed. Mater., 2013, 8  025012.

6. Felber, A.E., et al., Non-Viral Strategies for Nucleic Acid Delivery, Diss. ETH no. 21061, 2013.

7. Bosnjakovic, A., et al., A dendrimer-based immunosensor for improved capture and detection of tumor necrosis factor-α cytokine. Analytica Chimica Acta, 2012, 720(0): p. 118-125.

8. Hoang, B., et al., Block Copolymer Micelles Target Auger Electron Radiotherapy to the Nucleus of HER2-Positive Breast Cancer Cells, Biomacromolecules, 2012, 13(2), pp 455–465.

9. Chen, J., et al., PLLA-PEG-TCH-labeled bioactive molecule nanofibers for tissue engineering, International Journal of Nanomedicine, 2011, 6 2533–2542.

10. Felber, A.E., et al., siRNA nanocarriers based on methacrylic acid copolymers, Journal of Controlled Release, 2011, 152:1, P. 159-167.

11. Lee, H., et al., The Effects of Particle Size and Molecular Targeting on the Intratumoral and Subcellular Distribution of Polymeric Nanoparticles, Molecular Pharmaceutics, 2010, 7 (4), 1195-1208.

12. Zhou, S.,  Multifunctional Electrospun Nanofibers Incorporated with an Anti-infection Drug and Immobilized with Proteins, University of Manitoba, 2010.

13. Elliott, J.A., Targeted Drug Delivery with PEGylated Immuno-Niosomes, 25th Southern Biomedical Engineering Conference, 2009, p. 363-366.

14. Hoang, B., et al., Noninvasive Monitoring of the Fate of 111In-Labeled Block Copolymer Micelles by High Resolution and High Sensitivity MicroSPECT/CT Imaging, Mol. Pharmaceutics, 2009, 6(2) p: 581–592.

15. Jung, H., et al., Impact of Hapten Presentation on Antibody Binding at Lipid Membrane Interfaces, Biophysical Journal, 2008, 94(8), p: 3094-3103.

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